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Tuesday, June 29, 2010

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Product details

Series: Day Planners with 2019 and 2020 Calendars (Book 1)

Paperback: 108 pages

Publisher: CreateSpace Independent Publishing Platform (April 26, 2018)

Language: English

ISBN-10: 1717481124

ISBN-13: 978-1717481122

Product Dimensions:

7 x 0.2 x 10 inches

Shipping Weight: 9.4 ounces (View shipping rates and policies)

Average Customer Review:

4.6 out of 5 stars

3 customer reviews

Amazon Best Sellers Rank:

#91,573 in Books (See Top 100 in Books)

I love how you get to plan your priorities day by day.. the only thing I was mislead about was it not having motivational quotes when that’s one of the reasons I searched for a planner. Regardless cute and to the point

Love it!

Great for church members

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Download PDF , by Robert Marshall Utley

Saturday, June 26, 2010

Download PDF , by Robert Marshall Utley

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Product details

File Size: 2193 KB

Print Length: 254 pages

Simultaneous Device Usage: Unlimited

Publisher: New Word City, Inc.; 1 edition (September 1, 2015)

Publication Date: September 1, 2015

Sold by: Amazon Digital Services LLC

Language: English

ASIN: B014SEGC78

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#22,023 Paid in Kindle Store (See Top 100 Paid in Kindle Store)

I read this book over a week over morning breakfast and had a chance to chew on more than my cereal. It is well written and by two authors, Wilcomb Washburn on the early colonial period and Robert Utley on the post Civil War/ West of the Mississippi period. There has been much of late which tends to romanticize the American Indian and cast them as victims while whites are as victimizers. It was far more complex than that in that it was really a clash of civilizations, one moving into the industrial age, the other stone age. The book is well illustrated. It will serve as a primer for those interested in the history of the effects of Westward expansion on the American Indian.

This is another "poor Indians " book. There was clearly a lot of research in this book and much of it is true. But, it is written as if the Indians were always downtrodden and innocent of wrongdoing. For example, the Sibley expedition of 1862 resulted in the execution" n of a large number of Indian braves. Yes, that's true, but the authors skip over the fact that the Indians murdered more than 600 white settlers in Iowa and Minnesota, including women and children in a terrifying uprising.. The book also suggests that white men "raped the Indian women " they captured. No mention of what happened to white women captured by the Indians , repeated gang rapes, sexual mutilation and death.Also there is no mention of the tortures practiced by most of the tribes against white men. Like many books of this nature there is no balance. The whites are always described as evil and the Indians helpless. No mention t all in this book of Charlie Bent a murderous renegade who had a long record of depredations. This reader would like to see a bit more equality.

This is a very readable, topical history of the on-going state of war between the 1st group of settlers in this country, and the later, 2nd group of settlers. The narrative seems to do a fair story of highlighting both the genuine efforts and the recriminations of both sides. If there is any short-coming of this work, it is one of necessity. Many of the events and personalities feel a bit out of context, but to add the detail and background to accomplish that would require multiple volumes. This a s great starting place for any reader.

This is a good overview detailing the fate of the indigenous peoples of the current United States at the hands of the invading Northern Europeans. Warlike tribes fighting for dominance resisting all attempts at peaceful coexistence. Treachery and broken promises dot the landscape...on all sides.

This is a broad sweep of Indian wars in all regions of the US, from the founding of Jamestown (1608) and Plymouth (1620) through the final battle at Wounded Knee in 1891. The text is only 300 pages, so the details and backround of events are limited. It has no bibliography or maps, and many of the photos don't relate to the narrative, which doesn't help matters. For these reasons I can't give it top marks, but it is still a worthwhile read. This history is in two parts, the first written by Washburn, covers the expansion to the Mississippi up to 1846; and the second part is by Utley, covering the West.Both authors are knowledgeable of their subject and able to write an interesting account. As with all historical events, these wars take place in a broader context, and the authors provide some, though short. They do at least point out many of the reasons why the treaty system failed so miserably: greed, revenge, power, pride, ambition, incompetance, treachery, fear, confusion, ignorance, etc. It's all mentioned, but not developed. This is a consise history told with some measure of balance, without which no understanding of insane violence can be gained. Recommended as a starter.

This is an excellent overview of the wars between the British -- later the Americans -- and the Indians. Many books tell the story piecemeal, especially regarding the later wars with the plains and western tribes; this one tells it from beginning to end and yet manages to do so succinctly, compactly, and entertainingly. The account is balanced and objective, explaining the virtues and faults of both sides' positions.My quibble is that much of the book describes the movement of troops and tribes and the events of their battles and yet it contains, at least in my paperback edition, no maps to illustrate that. They would have been greatly helpful.

Very informative and easy reading. Lots of research and an understanding of the situations with each group of tribes. However, without a map foreach chapter it is difficult to understand where things are happening, distances involved, etc.. Seve3rtaal times I went to the computer to finda map because locations referred to were unknown or no longer using the same name.

This is a brief narrative of the fight between Europeans and their descendants and native Americans. It is straightforward, and generally objective. For those with little background in Native American history, this is a good Beginning. It will be less useful for those who have read widely on the subject.Daniel E. Spector, PhDUS Army Chemical Corps Historian, Retired

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Ebook Immunotherapy of Sarcoma

Tuesday, June 15, 2010

Ebook Immunotherapy of Sarcoma

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Immunotherapy of Sarcoma

Immunotherapy of Sarcoma


Immunotherapy of Sarcoma


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From the Back Cover

This book describes recent progress in the development of immunotherapies for advanced sarcoma, paying special attention to the potential role of manipulations of the sarcoma tumor immune microenvironment in achieving durable remissions. Readers will find a thorough overview of the state of the art in tumor immunology and immunotherapy as they relate to sarcoma. Among the topics addressed are advances in vaccine therapy; the value of adoptive transfer of cytokine-induced natural killer cells; the development of adoptive T cell strategies; and the scope for use of checkpoint inhibitors in patients with sarcoma, mirroring the tremendous breakthroughs made in other malignancies. Detailed information is provided on laboratory and clinical research, with analysis of outcomes of recent trials and identification of key challenges. There is every reason to believe that more effective and less toxic therapies for metastatic sarcoma can be attained by deepening our understanding of cancer immunology and building on the advances in immunotherapy for other solid tumors. In this context, Immunotherapy of Sarcoma will be of high interest for all medical oncologists responsible for the treatment of sarcoma patients.

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About the Author

Sandra D’Angelo is a medical oncologist specializing in the care of patients with soft tissue and bone sarcoma at Memorial Sloan Kettering Cancer Center. Her goal is to develop innovative ways to use the immune system to treat these rare cancers. Over the past few years she has been the principal investigator of numerous immunotherapy clinical trials.  Dr. D’Angelo has been building an immunology translational oncology program in sarcoma at Memorial Sloan Kettering Cancer Center. The basis of the program is systematically centered on the exploration of checkpoint blockade, combination strategies with checkpoint inhibitors, adoptive T cell therapy, and elucidation of biomarkers predictive of benefit to systemic immunotherapy. She is currently national principal investigator of the phase II trial of nivolumab with or without ipilimumab, conducted through the Alliance for Clinical Trials in Oncology Cooperative Group (A091401), which has great potential to advance our understanding of the application of immunotherapy in sarcoma. Seth M. Pollack is a physician-scientist whose research is entirely focused on the development of novel immunotherapies for patients with advanced sarcoma. The Pollack Lab has a particular interest in synovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL). The Lab has demonstrated that, like SS, MRCL tumors almost always homogeneously express a protein called NY-ESO-1, which is a member of the cancer-testes antigen family with features that make it an attractive target for immunotherapy. Using clinical grade reagents, the Pollack Lab developed a methodology for isolating and expanding NY-ESO-1-specific T cells from the peripheral blood of sarcoma patients and adoptively transferring these cells to specifically kill NY-ESO-1 expressing tumor cells. In a first clinical trial, clinical anti-tumor activity was unfortunately short lived but novel mechanisms of immune evasion were identified. Now, a new first-in-man trial is being planned to address these issues. The Pollack lab has also been characterizing the sarcoma immune microenvironment. Based on new and surprising findings, the lab has designed new, open, and enrolling investigator-sponsored trials for sarcoma patients using diverse immunotherapeutic strategies.      

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Product details

Hardcover: 152 pages

Publisher: Springer; 1st ed. 2019 edition (November 28, 2018)

Language: English

ISBN-10: 3319935291

ISBN-13: 978-3319935294

Product Dimensions:

6.5 x 0.6 x 9.4 inches

Shipping Weight: 1.1 pounds (View shipping rates and policies)

Average Customer Review:

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Amazon Best Sellers Rank:

#4,608,618 in Books (See Top 100 in Books)

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